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Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer’s Disease
BACKGROUND: The progressive neurodegenerative disorder Alzheimer’s disease (AD) manifests as loss of cognitive functions, and finally leads to death of the affected individual. AD may result from accumulation of amyloid plaques. These amyloid plaques comprising of amyloid-beta 42 (Aβ42) polypeptides...
Autores principales: | Cutler, Timothy, Sarkar, Ankita, Moran, Michael, Steffensmeier, Andrew, Puli, Oorvashi Roy, Mancini, Greg, Tare, Meghana, Gogia, Neha, Singh, Amit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569556/ https://www.ncbi.nlm.nih.gov/pubmed/26367392 http://dx.doi.org/10.1371/journal.pone.0137691 |
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