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The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates

There are currently no approved medical radiation countermeasures (MRC) to reduce the lethality of high-dose total body ionizing irradiation expected in nuclear emergencies. An ideal MRC would be effective even when administered well after radiation exposure and would counteract the effects of irrad...

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Detalles Bibliográficos
Autores principales: Krivokrysenko, Vadim I., Toshkov, Ilia A., Gleiberman, Anatoli S., Krasnov, Peter, Shyshynova, Inna, Bespalov, Ivan, Maitra, Ratan K., Narizhneva, Natalya V., Singh, Vijay K., Whitnall, Mark H., Purmal, Andrei A., Shakhov, Alexander N., Gudkov, Andrei V., Feinstein, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569586/
https://www.ncbi.nlm.nih.gov/pubmed/26367124
http://dx.doi.org/10.1371/journal.pone.0135388