High-resolution analysis of the human T-cell receptor repertoire

Unbiased dissection of T-cell receptor (TCR) repertoire diversity at the nucleotide level could provide important insights into human immunity. Here we show that TCR ligation-anchored-magnetically captured PCR (TCR-LA-MC PCR) identifies TCR α- and β-chain diversity without sequence-associated or qua...

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Detalles Bibliográficos
Autores principales: Ruggiero, Eliana, Nicolay, Jan P., Fronza, Raffaele, Arens, Anne, Paruzynski, Anna, Nowrouzi, Ali, Ürenden, Gökçe, Lulay, Christina, Schneider, Sven, Goerdt, Sergij, Glimm, Hanno, Krammer, Peter H., Schmidt, Manfred, von Kalle, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569693/
https://www.ncbi.nlm.nih.gov/pubmed/26324409
http://dx.doi.org/10.1038/ncomms9081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569693/
https://www.ncbi.nlm.nih.gov/pubmed/26324409
http://dx.doi.org/10.1038/ncomms9081

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