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BF(3)·Et(2)O Catalysed 4-Aryl-3-phenyl-benzopyrones, Pro-SERMs, and Their Characterization

We have synthesized the novel 4-(4-hydroxy-benzyl)-3-phenyl-chromen-2-one which is a precursor of SERMs with a smaller number of steps and good yield. Two methodologies for the synthesis have been worked out. Anhydrous BF(3)·Et(2)O catalyzed reaction was found to be selective for product formation w...

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Detalles Bibliográficos
Autores principales: Srivastava, Ambika, Singh, Pooja, Kumar, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569759/
https://www.ncbi.nlm.nih.gov/pubmed/26421007
http://dx.doi.org/10.1155/2015/527159