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Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development

Transcriptional program that drives human preimplantation development is largely unknown. Here, by using single-cell RNA sequencing of 348 oocytes, zygotes and single blastomeres from 2- to 3-day-old embryos, we provide a detailed analysis of the human preimplantation transcriptome. By quantifying t...

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Detalles Bibliográficos
Autores principales: Töhönen, Virpi, Katayama, Shintaro, Vesterlund, Liselotte, Jouhilahti, Eeva-Mari, Sheikhi, Mona, Madissoon, Elo, Filippini-Cattaneo, Giuditta, Jaconi, Marisa, Johnsson, Anna, Bürglin, Thomas R., Linnarsson, Sten, Hovatta, Outi, Kere, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569847/
https://www.ncbi.nlm.nih.gov/pubmed/26360614
http://dx.doi.org/10.1038/ncomms9207