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Extensive in silico analysis of Mimivirus coded Rab GTPase homolog suggests a possible role in virion membrane biogenesis

Rab GTPases are the key regulators of intracellular membrane trafficking in eukaryotes. Many viruses and intracellular bacterial pathogens have evolved to hijack the host Rab GTPase functions, mainly through activators and effector proteins, for their benefit. Acanthamoeba polyphaga mimivirus (APMV)...

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Detalles Bibliográficos
Autores principales: Zade, Amrutraj, Sengupta, Malavi, Kondabagil, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569851/
https://www.ncbi.nlm.nih.gov/pubmed/26441866
http://dx.doi.org/10.3389/fmicb.2015.00929