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Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion

During human placentation, mononuclear cytotrophoblasts fuse to form multinucleated syncytia ensuring hormonal production and nutrient exchanges between the maternal and fetal circulation. Syncytial formation is essential for the maintenance of pregnancy and for fetal growth. The cAMP signaling path...

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Detalles Bibliográficos
Autores principales: Gerbaud, Pascale, Taskén, Kjetil, Pidoux, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569887/
https://www.ncbi.nlm.nih.gov/pubmed/26441659
http://dx.doi.org/10.3389/fphar.2015.00202