Activation of acid-sensing ion channels by localized proton transient reveals their role in proton signaling

Extracellular transients of pH alterations likely mediate signal transduction in the nervous system. Neuronal acid-sensing ion channels (ASICs) act as sensors for extracellular protons, but the mechanism underlying ASIC activation remains largely unknown. Here, we show that, following activation of...

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Detalles Bibliográficos
Autores principales: Zeng, Wei-Zheng, Liu, Di-Shi, Liu, Lu, She, Liang, Wu, Long-Jun, Xu, Tian-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569896/
https://www.ncbi.nlm.nih.gov/pubmed/26370138
http://dx.doi.org/10.1038/srep14125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569896/
https://www.ncbi.nlm.nih.gov/pubmed/26370138
http://dx.doi.org/10.1038/srep14125

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