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Physicochemical characteristics of structurally determined metabolite-protein and drug-protein binding events with respect to binding specificity

To better understand and ultimately predict both the metabolic activities as well as the signaling functions of metabolites, a detailed understanding of the physical interactions of metabolites with proteins is highly desirable. Focusing in particular on protein binding specificity vs. promiscuity,...

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Detalles Bibliográficos
Autores principales: Korkuć, Paula, Walther, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569973/
https://www.ncbi.nlm.nih.gov/pubmed/26442281
http://dx.doi.org/10.3389/fmolb.2015.00051