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Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways

BACKGROUND: It is widely recognized that deep inspiration (DI), either before methacholine (MCh) challenge (Bronchoprotection, BP) or after MCh challenge (Bronchodilation, BD) protects against this challenge in healthy individuals, but not in asthmatics. Sulforaphane, a dietary antioxidant and antii...

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Detalles Bibliográficos
Autores principales: Brown, Robert H., Reynolds, Curt, Brooker, Allison, Talalay, Paul, Fahey, Jed W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570035/
https://www.ncbi.nlm.nih.gov/pubmed/26369337
http://dx.doi.org/10.1186/s12931-015-0253-z