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How to outsmart NK cell tolerance

Immune tolerance induced by regulatory mechanisms is an integral and fundamental part of immunity. In therapeutic settings, however, tolerance may significantly limit efficacy. Here, we summarize possible strategies to enhance therapeutic antibody dependent cellular cytotoxicity by overcoming NK cel...

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Detalles Bibliográficos
Autores principales: Terszowski, Grzegorz, Klein, Christian, Schmied, Laurent, Stern, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570122/
https://www.ncbi.nlm.nih.gov/pubmed/26405590
http://dx.doi.org/10.1080/2162402X.2015.1016708