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Depletion of B220(+)NK1.1(+) cells enhances the rejection of established melanoma by tumor-specific CD4(+) T cells

Five-year survival rates for patients diagnosed with metastatic melanoma are less than 5%. Adoptive cell transfer (ACT) has achieved an objective response of 50% by Response Evaluation Criteria in Solid Tumors (RECIST) in this patient population. For ACT to be maximally effective, the host must firs...

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Detalles Bibliográficos
Autores principales: Wilson, Kyle A, Goding, Stephen R, Neely, Harold R, Harris, Kristina M, Antony, Paul Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570124/
https://www.ncbi.nlm.nih.gov/pubmed/26405570
http://dx.doi.org/10.1080/2162402X.2015.1019196