Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled

Type I phosphatidylinositol phosphate kinase (PIP5K1) phosphorylates the head group of phosphatidylinositol 4-phosphate (PtdIns4P) to generate PtdIns4,5P(2), which plays important roles in a wide range of cellular functions including Wnt signalling. However, the lack of its structural information ha...

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Detalles Bibliográficos
Autores principales: Hu, Jian, Yuan, Qianying, Kang, Xue, Qin, Yuanbo, Li, Lin, Ha, Ya, Wu, Dianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570271/
https://www.ncbi.nlm.nih.gov/pubmed/26365782
http://dx.doi.org/10.1038/ncomms9205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570271/
https://www.ncbi.nlm.nih.gov/pubmed/26365782
http://dx.doi.org/10.1038/ncomms9205

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