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Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled
Type I phosphatidylinositol phosphate kinase (PIP5K1) phosphorylates the head group of phosphatidylinositol 4-phosphate (PtdIns4P) to generate PtdIns4,5P(2), which plays important roles in a wide range of cellular functions including Wnt signalling. However, the lack of its structural information ha...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570271/ https://www.ncbi.nlm.nih.gov/pubmed/26365782 http://dx.doi.org/10.1038/ncomms9205 |