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Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of Cd151

Altered expression of the tetraspanin CD151 is associated with skin tumorigenesis; however, whether CD151 is causally involved in the tumorigenic process is not known. To evaluate its role in tumor formation, we subjected epidermis-specific Cd151 knockout mice to chemical skin carcinogenesis. Mice l...

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Detalles Bibliográficos
Autores principales: Sachs, Norman, Secades, Pablo, van Hulst, Laura, Song, Ji-Ying, Sonnenberg, Arnoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570276/
https://www.ncbi.nlm.nih.gov/pubmed/23792458
http://dx.doi.org/10.1038/jid.2013.280