L(59) TGF-β LAP degradation products serve as a promising blood biomarker for liver fibrogenesis in mice

BACKGROUND: Hepatic fibrosis, which is the excessive accumulation of extracellular matrices (ECMs) produced mainly from activated hepatic stellate cells (HSCs), develops to cirrhosis over several decades. There are no validated biomarkers that can non-invasively monitor excessive production of ECM (...

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Detalles Bibliográficos
Autores principales: Hara, Mitsuko, Inoue, Ikuyo, Yamazaki, Yuta, Kirita, Akiko, Matsuura, Tomokazu, Friedman, Scott L., Rifkin, Daniel B., Kojima, Soichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570586/
https://www.ncbi.nlm.nih.gov/pubmed/26379781
http://dx.doi.org/10.1186/s13069-015-0034-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570586/
https://www.ncbi.nlm.nih.gov/pubmed/26379781
http://dx.doi.org/10.1186/s13069-015-0034-9

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