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Genetic predisposition of donors affects the allograft outcome in kidney transplantation: Single-nucleotide polymorphism of aquaporin-11

BACKGROUND: Aquaporin-11 (AQP11) is a novel member of the aquaporin family. Disruption of the murine Aqp11 gene causes severe proximal tubular injury and renal failure. The rs2276415 (G>A) single-nucleotide polymorphism in the human AQP11 gene results in glycine to serine substitution in a functi...

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Detalles Bibliográficos
Autores principales: Park, Ji In, Yang, Seung Hee, Lee, Jung Pyo, Yoo, Seong Ho, Kim, Yon Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570646/
https://www.ncbi.nlm.nih.gov/pubmed/26484019
http://dx.doi.org/10.1016/j.krcp.2015.01.002