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Uridine supplementation exerts anti-inflammatory and anti-fibrotic effects in an animal model of pulmonary fibrosis

RATIONALE: Pulmonary fibrosis is a progressive disease with only few treatment options available at the moment. Recently, the nucleoside uridine has been shown to exert anti-inflammatory effects in different animal models, e.g. in acute lung injury or bronchial asthma. METHOD: Therefore, we investig...

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Detalles Bibliográficos
Autores principales: Cicko, Sanja, Grimm, Melanie, Ayata, Korcan, Beckert, Jessica, Meyer, Anja, Hossfeld, Madelon, Zissel, Gernot, Idzko, Marco, Müller, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570657/
https://www.ncbi.nlm.nih.gov/pubmed/26369416
http://dx.doi.org/10.1186/s12931-015-0264-9