Transcriptome analysis of complex I-deficient patients reveals distinct expression programs for subunits and assembly factors of the oxidative phosphorylation system

BACKGROUND: Transcriptional control of mitochondrial metabolism is essential for cellular function. A better understanding of this process will aid the elucidation of mitochondrial disorders, in particular of the many genetically unsolved cases of oxidative phosphorylation (OXPHOS) deficiency. Yet,...

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Detalles Bibliográficos
Autores principales: van der Lee, Robin, Szklarczyk, Radek, Smeitink, Jan, Smeets, Hubert J M, Huynen, Martijn A., Vogel, Rutger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570683/
https://www.ncbi.nlm.nih.gov/pubmed/26369791
http://dx.doi.org/10.1186/s12864-015-1883-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570683/
https://www.ncbi.nlm.nih.gov/pubmed/26369791
http://dx.doi.org/10.1186/s12864-015-1883-8

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