Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer

INTRODUCTION: It has been shown in some articles that genetic and epigenetic abnormalities cannot only be found in tumor tissues but also in adjacent regions that appear histologically normal. This phenomenon is metaphorically called field cancerization or field defect. Field cancerization is regard...

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Detalles Bibliográficos
Autores principales: Spitzwieser, Melanie, Holzweber, Elisabeth, Pfeiler, Georg, Hacker, Stefan, Cichna-Markl, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570691/
https://www.ncbi.nlm.nih.gov/pubmed/26370119
http://dx.doi.org/10.1186/s13058-015-0637-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570691/
https://www.ncbi.nlm.nih.gov/pubmed/26370119
http://dx.doi.org/10.1186/s13058-015-0637-5

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