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The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation

As the Lyme disease bacterium Borrelia burgdorferi traverses its enzootic cycle, alternating between a tick vector and a vertebrate host, the spirochete must adapt and persist in the tick midgut under prolonged nutrient stress between blood meals. In this study, we examined the role of the stringent...

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Detalles Bibliográficos
Autores principales: Drecktrah, Dan, Lybecker, Meghan, Popitsch, Niko, Rescheneder, Philipp, Hall, Laura S., Samuels, D. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570706/
https://www.ncbi.nlm.nih.gov/pubmed/26371761
http://dx.doi.org/10.1371/journal.ppat.1005160