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Copy number alterations detected by whole-exome and whole-genome sequencing of esophageal adenocarcinoma
BACKGROUND: Esophageal adenocarcinoma (EA) is among the leading causes of cancer mortality, especially in developed countries. A high level of somatic copy number alterations (CNAs) accumulates over the decades in the progression from Barrett’s esophagus, the precursor lesion, to EA. Accurate identi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570720/ https://www.ncbi.nlm.nih.gov/pubmed/26374103 http://dx.doi.org/10.1186/s40246-015-0044-0 |