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A new paradigm for tumor immune escape: β-catenin-driven immune exclusion
Increasing evidence is emerging that immunotherapeutic interventions, including checkpoint blockade, are predominantly effective in patients with a pre-existing T cell-inflamed tumor microenvironment. Understanding the mechanisms leading to a non-T cell-inflamed microenvironment are crucial for the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570721/ https://www.ncbi.nlm.nih.gov/pubmed/26380088 http://dx.doi.org/10.1186/s40425-015-0089-6 |