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Radix Scrophulariae extracts (harpagoside) suppresses hypoxia-induced microglial activation and neurotoxicity

BACKGROUND: Hypoxia could lead to microglia activation and inflammatory mediators’ overproduction. These inflammatory molecules could amplify the neuroinflammatory process and exacerbate neuronal injury. The aim of this study is to find out whether harpagoside could reduce hypoxia-induced microglia...

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Detalles Bibliográficos
Autores principales: Sheu, Shiow-Yunn, Hong, Yi-Wen, Sun, Jui-Sheng, Liu, Man-Hai, Chen, Ching-Yun, Ke, Cherng-Jyh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570756/
https://www.ncbi.nlm.nih.gov/pubmed/26370415
http://dx.doi.org/10.1186/s12906-015-0842-x