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Fibroblast-Derived Extracellular Matrices: An Alternative Cell Culture System That Increases Metastatic Cellular Properties

Poor survival rates from lung cancer can largely be attributed to metastatic cells that invade and spread throughout the body. The tumor microenvironment (TME) is composed of multiple cell types, as well as non-cellular components. The TME plays a critical role in the development of metastatic cance...

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Detalles Bibliográficos
Autores principales: Scherzer, Michael T., Waigel, Sabine, Donninger, Howard, Arumugam, Vennila, Zacharias, Wolfgang, Clark, Geoffrey, Siskind, Leah J., Soucy, Patricia, Beverly, Levi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570771/
https://www.ncbi.nlm.nih.gov/pubmed/26371754
http://dx.doi.org/10.1371/journal.pone.0138065