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The Role of Sirt1 in Bile Acid Regulation during Calorie Restriction in Mice
Sirtuin 1 (Sirt1) is an NAD(+)-dependent protein deacetylase that is proposed to mediate many health-promoting effects of calorie restriction (CR). We recently reported that short-term CR increased the bile acid (BA) pool size in mice, likely due to increased BA synthesis in liver. Given the importa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570809/ https://www.ncbi.nlm.nih.gov/pubmed/26372644 http://dx.doi.org/10.1371/journal.pone.0138307 |