The Role of Sirt1 in Bile Acid Regulation during Calorie Restriction in Mice

Sirtuin 1 (Sirt1) is an NAD(+)-dependent protein deacetylase that is proposed to mediate many health-promoting effects of calorie restriction (CR). We recently reported that short-term CR increased the bile acid (BA) pool size in mice, likely due to increased BA synthesis in liver. Given the importa...

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Detalles Bibliográficos
Autores principales: Fu, Zidong Donna, Cui, Julia Yue, Klaassen, Curtis D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570809/
https://www.ncbi.nlm.nih.gov/pubmed/26372644
http://dx.doi.org/10.1371/journal.pone.0138307

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