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Control of crosslinking for tailoring collagen-based scaffolds stability and mechanics
We provide evidence to show that the standard reactant concentrations used in tissue engineering to cross-link collagen-based scaffolds are up to 100 times higher than required for mechanical integrity in service, and stability against degradation in an aqueous environment. We demonstrate this with...
Autores principales: | Davidenko, N., Schuster, C.F., Bax, D.V., Raynal, N., Farndale, R.W., Best, S.M., Cameron, R.E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570933/ https://www.ncbi.nlm.nih.gov/pubmed/26213371 http://dx.doi.org/10.1016/j.actbio.2015.07.034 |
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