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An Enterovirus-Like RNA Construct for Colon Cancer Suicide Gene Therapy

BACKGROUND: In gene therapy, the use of RNA molecules as therapeutic agents has shown advantages over plasmid DNA, including higher levels of safety. However, transient nature of RNA has been a major obstacle in application of RNA in gene therapy. METHODS: Here, we used the internal ribosomal entry...

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Detalles Bibliográficos
Autores principales: Rasekhian, Mahsa, Teimoori-Toolabi, Ladan, Amini, Safieh, Azadmanesh, Kayhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571007/
https://www.ncbi.nlm.nih.gov/pubmed/26025964
http://dx.doi.org/10.7508/ibj.2015.03.001