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Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis

During embryonic development, hematopoietic cells develop by a process of endothelial-to hematopoietic transition of a specialized population of endothelial cells. These hemogenic endothelium (HE) cells in turn develop from a primitive population of FLK1(+) mesodermal cells. Endoglin (ENG) is an acc...

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Detalles Bibliográficos
Autores principales: Nasrallah, Rabab, Knezevic, Kathy, Thai, Thuan, Thomas, Shane R., Göttgens, Berthold, Lacaud, Georges, Kouskoff, Valerie, Pimanda, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571086/
https://www.ncbi.nlm.nih.gov/pubmed/25979706
http://dx.doi.org/10.1242/bio.011494