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BAZ1B is dispensable for H2AX phosphorylation on Tyrosine 142 during spermatogenesis

Meiosis is precisely regulated by the factors involved in DNA damage response in somatic cells. Among them, phosphorylation of H2AX on Serine 139 (γH2AX) is an essential signal for the silencing of unsynapsed sex chromosomes during male meiosis. However, it remains unknown how adjacent H2AX phosphor...

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Detalles Bibliográficos
Autores principales: Broering, Tyler J., Wang, Yuan-Liang, Pandey, Ram Naresh, Hegde, Rashmi S., Wang, Shao-Chun, Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571090/
https://www.ncbi.nlm.nih.gov/pubmed/25979708
http://dx.doi.org/10.1242/bio.011734