Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans

AIMS: Monocytes play critical roles in tissue injury and repair following acute myocardial infarction (AMI). Specifically targeting inflammatory monocytes in experimental models leads to reduced infarct size and improved healing. However, data from humans are sparse, and it remains unclear whether m...

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Detalles Bibliográficos
Autores principales: Ruparelia, Neil, Godec, Jernej, Lee, Regent, Chai, Joshua T., Dall'Armellina, Erica, McAndrew, Debra, Digby, Janet E., Forfar, J. Colin, Prendergast, Bernard D., Kharbanda, Rajesh K., Banning, Adrian P., Neubauer, Stefan, Lygate, Craig A., Channon, Keith M., Haining, Nicholas W., Choudhury, Robin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571177/
https://www.ncbi.nlm.nih.gov/pubmed/25982896
http://dx.doi.org/10.1093/eurheartj/ehv195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571177/
https://www.ncbi.nlm.nih.gov/pubmed/25982896
http://dx.doi.org/10.1093/eurheartj/ehv195

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