How Leiomodin and Tropomodulin use a common fold for different actin assembly functions

How proteins sharing a common fold have evolved different functions is a fundamental question in biology. Tropomodulins (Tmods) are prototypical actin filament pointed-end-capping proteins, whereas their homologues, Leiomodins (Lmods), are powerful filament nucleators. We show that Tmods and Lmods d...

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Detalles Bibliográficos
Autores principales: Boczkowska, Malgorzata, Rebowski, Grzegorz, Kremneva, Elena, Lappalainen, Pekka, Dominguez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571291/
https://www.ncbi.nlm.nih.gov/pubmed/26370058
http://dx.doi.org/10.1038/ncomms9314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571291/
https://www.ncbi.nlm.nih.gov/pubmed/26370058
http://dx.doi.org/10.1038/ncomms9314

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