The disease-linked Glu-26-Lys mutant version of Coronin 1A exhibits pleiotropic and pathway-specific signaling defects

Coronin 1A (Coro1A) is involved in cytoskeletal and signaling events, including the regulation of Rac1 GTPase– and myosin II–dependent pathways. Mutations that generate truncated or unstable Coro1A proteins cause immunodeficiencies in both humans and rodents. However, in the case of the peripheral T...

Descripción completa

Detalles Bibliográficos
Autores principales: Ojeda, Virginia, Robles-Valero, Javier, Barreira, María, Bustelo, Xosé R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571328/
https://www.ncbi.nlm.nih.gov/pubmed/26108624
http://dx.doi.org/10.1091/mbc.E15-01-0052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571328/
https://www.ncbi.nlm.nih.gov/pubmed/26108624
http://dx.doi.org/10.1091/mbc.E15-01-0052

Ejemplares similares