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Phosphorylation and SCF-mediated degradation regulate CREB-H transcription of metabolic targets
CREB‑H, an endoplasmic reticulum–anchored transcription factor, plays a key role in regulating secretion and in metabolic and inflammatory pathways, but how its activity is modulated remains unclear. We examined processing of the nuclear active form and identified a motif around S87–S90 with homolog...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571331/ https://www.ncbi.nlm.nih.gov/pubmed/26108621 http://dx.doi.org/10.1091/mbc.E15-04-0247 |