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Crystal structures of vortioxetine and its methanol monosolvate

Vortioxetine, C(18)H(22)N(2)S, (1), systematic name 1-{2-[(2,4-di­methyl­phen­yl)sulfan­yl]phen­yl}piperazine, a new drug used to treat patients with major depressive disorder, has been crystallized as the free base and its methanol monosolvate, C(18)H(22)N(2)S·CH(3)OH, (2). In both structures, the...

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Detalles Bibliográficos
Autores principales: Zhou, Xin-Bo, Gu, Jian-Ming, Sun, Meng-ying, Hu, Xiu-Rong, Wu, Su-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571347/
https://www.ncbi.nlm.nih.gov/pubmed/26396746
http://dx.doi.org/10.1107/S2056989015012256