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Altered Levels of Zinc and N-methyl-D-aspartic Acid Receptor Underlying Multiple Organ Dysfunctions After Severe Trauma

BACKGROUND: Severe trauma can cause secondary multiple organ dysfunction syndrome (MODS) and death. Oxidative stress and/or excitatory neurotoxicity are considered as the final common pathway in nerve cell injuries. Zinc is the cofactor of the redox enzyme, and the effect of the excitatory neurotoxi...

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Detalles Bibliográficos
Autores principales: Wang, Guanghuan, Yu, Xiaojun, Wang, Dian, Xu, Xiaohu, Chen, Guang, Jiang, Xuewu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571529/
https://www.ncbi.nlm.nih.gov/pubmed/26335029
http://dx.doi.org/10.12659/MSM.895075