MicroRNAs downregulated in neuropathic pain regulate MeCP2 and BDNF related to pain sensitivity

Nerve injury induces chronic pain and dysregulation of microRNAs in dorsal root ganglia (DRG). Several downregulated microRNAs are predicted to target Mecp2. MECP2 mutations cause Rett syndrome and these patients report decreased pain perception. We confirmed MeCP2 upregulation in DRG following nerv...

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Detalles Bibliográficos
Autores principales: Manners, Melissa T., Tian, Yuzhen, Zhou, Zhaolan, Ajit, Seena K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571540/
https://www.ncbi.nlm.nih.gov/pubmed/26448907
http://dx.doi.org/10.1016/j.fob.2015.08.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571540/
https://www.ncbi.nlm.nih.gov/pubmed/26448907
http://dx.doi.org/10.1016/j.fob.2015.08.010

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