Dexmedetomidine-Induced Contraction in the Isolated Endothelium-Denuded Rat Aorta Involves PKC-δ-mediated JNK Phosphorylation

Vasoconstriction mediated by the highly selective alpha-2 adrenoceptor agonist dexmedetomidine leads to transiently increased blood pressure and severe hypertension. The dexmedetomidine-induced contraction involves the protein kinase C (PKC)-mediated pathway. However, the main PKC isoform involved i...

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Detalles Bibliográficos
Autores principales: Yu, Jongsun, Ok, Seong-Ho, Kim, Won Ho, Cho, Hyunhoo, Park, Jungchul, Shin, il-Woo, Lee, Heon Keun, Chung, Young-Kyun, Choi, Mun-Jeoung, Kwon, Seong-Chun, Sohn, Ju-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571550/
https://www.ncbi.nlm.nih.gov/pubmed/26392810
http://dx.doi.org/10.7150/ijms.11952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571550/
https://www.ncbi.nlm.nih.gov/pubmed/26392810
http://dx.doi.org/10.7150/ijms.11952

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