Cargando…

Corticotropin-Releasing Factor Mediates Pain-Induced Anxiety through the ERK1/2 Signaling Cascade in Locus Coeruleus Neurons

BACKGROUND: The corticotropin-releasing factor is a stress-related neuropeptide that modulates locus coeruleus activity. As locus coeruleus has been involved in pain and stress-related patologies, we tested whether the pain-induced anxiety is a result of the corticotropin-releasing factor released i...

Descripción completa

Detalles Bibliográficos
Autores principales: Borges, Gisela Patrícia, Micó, Juan Antonio, Neto, Fani Lourença, Berrocoso, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571622/
https://www.ncbi.nlm.nih.gov/pubmed/25716783
http://dx.doi.org/10.1093/ijnp/pyv019