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NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation

BACKGROUND: Evidence from both clinical and experimental research indicates that the immune-brain interaction plays a pivotal role in the pathophysiology of depression. A multi-protein complex of the innate immune system, the NLRP3 inflammasome regulates cleavage and secretion of proinflammatory cyt...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Liu, Lei, Liu, Yun-Zi, Shen, Xiao-Liang, Wu, Teng-Yun, Zhang, Ting, Wang, Wei, Wang, Yun-Xia, Jiang, Chun-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571628/
https://www.ncbi.nlm.nih.gov/pubmed/25603858
http://dx.doi.org/10.1093/ijnp/pyv006