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NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation
BACKGROUND: Evidence from both clinical and experimental research indicates that the immune-brain interaction plays a pivotal role in the pathophysiology of depression. A multi-protein complex of the innate immune system, the NLRP3 inflammasome regulates cleavage and secretion of proinflammatory cyt...
Autores principales: | Zhang, Yi, Liu, Lei, Liu, Yun-Zi, Shen, Xiao-Liang, Wu, Teng-Yun, Zhang, Ting, Wang, Wei, Wang, Yun-Xia, Jiang, Chun-Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571628/ https://www.ncbi.nlm.nih.gov/pubmed/25603858 http://dx.doi.org/10.1093/ijnp/pyv006 |
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