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M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice

Cholinergic nervous system regulates liver injury. However, the role of M1 muscarinic receptors (M1R) in modulating chronic liver injury is uncertain. To address this gap in knowledge we treated M1R-deficient and WT mice with azoxymethane (AOM) for six weeks and assessed liver injury responses 14 we...

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Detalles Bibliográficos
Autores principales: Rachakonda, Vikrant, Jadeja, Ravirajsinh N., Urrunaga, Nathalie H., Shah, Nirish, Ahmad, Daniel, Cheng, Kunrong, Twaddell, William S., Raufman, Jean-Pierre, Khurana, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571652/
https://www.ncbi.nlm.nih.gov/pubmed/26374068
http://dx.doi.org/10.1038/srep14110