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M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice
Cholinergic nervous system regulates liver injury. However, the role of M1 muscarinic receptors (M1R) in modulating chronic liver injury is uncertain. To address this gap in knowledge we treated M1R-deficient and WT mice with azoxymethane (AOM) for six weeks and assessed liver injury responses 14 we...
Autores principales: | Rachakonda, Vikrant, Jadeja, Ravirajsinh N., Urrunaga, Nathalie H., Shah, Nirish, Ahmad, Daniel, Cheng, Kunrong, Twaddell, William S., Raufman, Jean-Pierre, Khurana, Sandeep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571652/ https://www.ncbi.nlm.nih.gov/pubmed/26374068 http://dx.doi.org/10.1038/srep14110 |
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