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Peak BMP Responses in the Drosophila Embryo Are Dependent on the Activation of Integrin Signaling

Within a 3D tissue, cells need to integrate signals from growth factors, such as BMPs, and the extracellular matrix (ECM) to coordinate growth and differentiation. Here, we use the Drosophila embryo as a model to investigate how BMP responses are influenced by a cell’s local ECM environment. We show...

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Detalles Bibliográficos
Autores principales: Sawala, Annick, Scarcia, Margherita, Sutcliffe, Catherine, Wilcockson, Scott G., Ashe, Hilary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571823/
https://www.ncbi.nlm.nih.gov/pubmed/26321638
http://dx.doi.org/10.1016/j.celrep.2015.08.012