Tetracycline-grafted PLGA nanoparticles as bone-targeting drug delivery system

PURPOSE: Nanoparticles (NPs) that target bone tissue were developed using poly(lactic-co-glycolic acid) (PLGA) copolymers and tetracycline (TC)-based bone-targeting moieties. These NPs are expected to enable the transport of drugs, such as simvastatin (SIM), for the treatment of osteoporosis. METHOD...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Liu, Jun, Tao, Shan, Chai, Guihong, Wang, Jianwei, Hu, Fu-Qiang, Yuan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571930/
https://www.ncbi.nlm.nih.gov/pubmed/26388691
http://dx.doi.org/10.2147/IJN.S88798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571930/
https://www.ncbi.nlm.nih.gov/pubmed/26388691
http://dx.doi.org/10.2147/IJN.S88798

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