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Tetracycline-grafted PLGA nanoparticles as bone-targeting drug delivery system

PURPOSE: Nanoparticles (NPs) that target bone tissue were developed using poly(lactic-co-glycolic acid) (PLGA) copolymers and tetracycline (TC)-based bone-targeting moieties. These NPs are expected to enable the transport of drugs, such as simvastatin (SIM), for the treatment of osteoporosis. METHOD...

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Detalles Bibliográficos
Autores principales:	Wang, Hua, Liu, Jun, Tao, Shan, Chai, Guihong, Wang, Jianwei, Hu, Fu-Qiang, Yuan, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571930/ https://www.ncbi.nlm.nih.gov/pubmed/26388691 http://dx.doi.org/10.2147/IJN.S88798

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