Pre-steady-state Kinetic Analysis of a Family D DNA Polymerase from Thermococcus sp. 9°N Reveals Mechanisms for Archaeal Genomic Replication and Maintenance

Family D DNA polymerases (polDs) have been implicated as the major replicative polymerase in archaea, excluding the Crenarchaeota branch, and bear little sequence homology to other DNA polymerase families. Here we report a detailed kinetic analysis of nucleotide incorporation and exonuclease activit...

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Detalles Bibliográficos
Autores principales: Schermerhorn, Kelly M., Gardner, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571936/
https://www.ncbi.nlm.nih.gov/pubmed/26160179
http://dx.doi.org/10.1074/jbc.M115.662841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571936/
https://www.ncbi.nlm.nih.gov/pubmed/26160179
http://dx.doi.org/10.1074/jbc.M115.662841

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