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Strategies for fine-mapping complex traits

Genome-wide association studies (GWAS) have identified thousands of robust and replicable genetic associations for complex disease. However, the identification of the causal variants that underlie these associations has been more difficult. This problem of fine-mapping association signals predates G...

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Detalles Bibliográficos
Autores principales: Spain, Sarah L., Barrett, Jeffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572002/
https://www.ncbi.nlm.nih.gov/pubmed/26157023
http://dx.doi.org/10.1093/hmg/ddv260