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Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria

Evidence indicates that Parkinson’s disease (PD), in addition to having a genetic aetiology, has an environmental component that contributes to disease onset and progression. The exact nature of any environmental agent contributing to PD is unknown in most cases. Given its similarity to paraquat, an...

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Detalles Bibliográficos
Autores principales: Nisar, R., Hanson, P. S., He, L., Taylor, R. W., Blain, P. G., Morris, C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572080/
https://www.ncbi.nlm.nih.gov/pubmed/25693864
http://dx.doi.org/10.1007/s00204-015-1453-5